EMC6

Across TCGA cell cohorts, EMC6 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,691 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible EMC6-associated GO terms across cancer lineages are RNA folding, Mitochondrial ribosome assembly, and Peptidyl-methionine modification. Each is linked with EMC6 in more than 14 cancer types. Because this analysis shows association rather than direction, both EMC6-to-partner and partner-to-EMC6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA folding grouped by EMC6-low versus EMC6-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EMC6→partner) and Y-score (partner→EMC6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	RNA folding →	+0.129	+0.978	<.001	<.001	3	15
BLOOD_Lymphoma	Mitochondrial ribosome assembly →	+0.121	+1.378	<.001	<.001	3	11
LIVER	Peptidyl-methionine modification →	+0.248	+0.433	.001	.009	3	11
BONE	Regulation of establishment of protein localization to telomere →	+0.134	+1.071	.001	<.001	3	11
OESOPHAGUS	rRNA modification →	+0.092	+0.928	<.001	<.001	3	10
BONE	Energy coupled proton transmembrane transport, against electrochemical gradient →	+0.135	+1.224	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,691 associations by consensus.

RNA folding by EMC6 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →