EMC4

Across TCGA patient cohorts, EMC4 protein abundance is significantly associated with the RNA expression of many other genes, with 12,591 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EMC4-associated genes across cancer lineages are SNORD17, HSPG2, and DCHS1. Each is linked with EMC4 in more than 3 cancer types. Because this analysis shows association rather than direction, both EMC4-to-partner and partner-to-EMC4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EMC4 versus SNORD17 in UCEC, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EMC4→partner) and Y-score (partner→EMC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNORD17 →	-2.398	-0.472	<.001	<.001	3	4
BRCA	HSPG2 →	-0.964	-0.314	.005	.004	3	4
UCEC	DCHS1 →	-0.897	-0.355	<.001	.002	3	4
CCRCC	TLN2 →	-0.601	-0.181	<.001	<.001	3	4
CCRCC	MARCHF9 →	-0.499	-0.212	.003	.003	3	4
CCRCC	STAG1 →	-0.345	-0.308	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,591 associations by consensus.

EMC4 vs SNORD17 — UCEC

Explore this scatter interactively →