EMC3

Across TCGA patient cohorts, EMC3 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,683 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible EMC3-associated proteins across cancer lineages are PDCD6IP, ANKRD28, and PDIA6. Each is linked with EMC3 in more than 6 cancer types. Because this analysis shows association rather than direction, both EMC3-to-partner and partner-to-EMC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EMC3 versus PDCD6IP in PDAC, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EMC3→partner) and Y-score (partner→EMC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	PDCD6IP →	+0.250	+0.309	<.001	<.001	3	6
OV	ANKRD28 →	+0.245	+0.478	.006	.002	2	7
BRCA	PDIA6 →	-0.307	-0.465	.001	<.001	3	4
LSCC	RAF1 →	+0.197	+0.320	.001	<.001	3	4
BRCA	ARL8B →	+0.377	+0.341	.001	.008	3	4
LSCC	CRELD2 →	-0.487	-0.287	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,683 associations by consensus.

EMC3 vs PDCD6IP — PDAC

Explore this scatter interactively →