EMC3

Across TCGA patient cohorts, EMC3 protein abundance is significantly associated with the protein abundance of many other proteins, with 16,352 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EMC3-associated proteins across cancer lineages are EMC4, EMC1, and EMC10. Each is linked with EMC3 in more than 9 cancer types. Because this analysis shows association rather than direction, both EMC3-to-partner and partner-to-EMC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EMC3 versus EMC4 in UCEC, with a Pearson correlation of 0.79.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EMC3→partner) and Y-score (partner→EMC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EMC4 →	+0.540	+0.446	<.001	<.001	3	10
UCEC	EMC1 →	+0.497	+0.555	<.001	<.001	3	9
UCEC	EMC10 →	+0.433	+0.495	<.001	<.001	3	9
BRCA	TMEM33 →	+0.765	+0.532	<.001	<.001	3	9
UCEC	ZMPSTE24 →	+0.828	+0.525	<.001	<.001	3	9
UCEC	EMC7 →	+0.519	+0.495	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,352 associations by consensus.

EMC3 vs EMC4 — UCEC

Explore this scatter interactively →