EMC3

Across TCGA cell cohorts, EMC3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,759 significant associations in total. BONE shows the largest number of these associations.

The most reproducible EMC3-associated GO terms across cancer lineages are Glycolipid catabolic process, Endoplasmic reticulum to Golgi vesicle-mediated transport, and Amyloid-beta clearance by transcytosis. Each is linked with EMC3 in more than 11 cancer types. Because this analysis shows association rather than direction, both EMC3-to-partner and partner-to-EMC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Glycolipid catabolic process grouped by EMC3-low versus EMC3-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EMC3→partner) and Y-score (partner→EMC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Glycolipid catabolic process →	+0.193	+0.748	<.001	<.001	3	12
SOFT_TISSUE	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.090	+0.924	<.001	<.001	3	12
KIDNEY	Amyloid-beta clearance by transcytosis →	+0.167	+1.093	<.001	.001	3	11
SOFT_TISSUE	Regulation of L-glutamate import across plasma membrane →	+0.176	+0.785	<.001	<.001	3	11
LIVER	Protein exit from endoplasmic reticulum →	+0.138	+0.778	.001	.008	3	11
SOFT_TISSUE	Lysosomal lumen acidification →	+0.135	+0.782	<.001	.001	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,759 associations by consensus.

Glycolipid catabolic process by EMC3 expression — SOFT_TISSUE

Explore this box plot interactively →