EMC1

Across TCGA patient cohorts, EMC1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,489 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible EMC1-associated genes across cancer lineages are CD34, CSDC2, and TNS2. Each is linked with EMC1 in more than 5 cancer types. Because this analysis shows association rather than direction, both EMC1-to-partner and partner-to-EMC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EMC1 versus CD34 in CCRCC, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EMC1→partner) and Y-score (partner→EMC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	CD34 →	-1.008	-0.343	<.001	<.001	3	6
CCRCC	CSDC2 →	-1.374	-0.294	.003	.002	3	6
BRCA	TNS2 →	-0.979	-0.336	<.001	<.001	3	5
BRCA	PLSCR4 →	-0.857	-0.279	<.001	<.001	3	5
UCEC	SYNE1 →	-0.868	-0.275	<.001	<.001	3	5
UCEC	HSPG2 →	-0.829	-0.332	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,489 associations by consensus.

EMC1 vs CD34 — CCRCC

Explore this scatter interactively →