EMC1

Across TCGA cell cohorts, EMC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,853 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EMC1-associated GO terms across cancer lineages are Mitotic chromosome condensation, Multi-pass transmembrane protein insertion into ER membrane, and Response to heat. Each is linked with EMC1 in more than 13 cancer types. Because this analysis shows association rather than direction, both EMC1-to-partner and partner-to-EMC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic chromosome condensation grouped by EMC1-low versus EMC1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EMC1→partner) and Y-score (partner→EMC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Mitotic chromosome condensation →	+0.196	+1.171	<.001	<.001	3	14
BONE	Multi-pass transmembrane protein insertion into ER membrane →	+0.138	+1.097	<.001	<.001	3	14
BLOOD_Myeloma	Response to heat →	+0.082	+1.051	<.001	.002	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of telomerase RNA localization to Cajal body →	+0.097	+0.818	.001	.003	3	14
BREAST	Protein insertion into ER membrane →	+0.098	+1.068	<.001	<.001	3	13
STOMACH	Regulation of intracellular transport →	+0.060	+0.980	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,853 associations by consensus.

Mitotic chromosome condensation by EMC1 expression — BREAST

Explore this box plot interactively →