EMB

Across TCGA patient cohorts, EMB protein abundance is significantly associated with the RNA expression of many other genes, with 12,521 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EMB-associated genes across cancer lineages are CD33, DOK3, and WAS. Each is linked with EMB in more than 3 cancer types. Because this analysis shows association rather than direction, both EMB-to-partner and partner-to-EMB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EMB versus CD33 in CCRCC, with a Pearson correlation of 0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EMB→partner) and Y-score (partner→EMB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	CD33 →	+0.838	+0.587	.001	<.001	3	4
BRCA	DOK3 →	+0.856	+0.506	<.001	.003	3	4
UCEC	WAS →	+1.019	+1.021	.009	.008	3	4
BRCA	SNX20 →	+0.866	+0.452	.002	.006	3	4
GBM	CCL13 →	+1.252	+0.539	<.001	<.001	3	4
BRCA	CSF1R →	+0.781	+0.419	.007	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,521 associations by consensus.

EMB vs CD33 — CCRCC

Explore this scatter interactively →