ELP6

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, ELP6 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ELP6 data layer compared with 23 for mass-spec protein.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher ELP6 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated ELP6 expression acts as an unfavorable survival marker, although some lineages such as PDAC show a favorable association.

GBM, PDAC, and CCRCC are the cancer types where ELP6 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
GBMDFSTertileAll0.2340.587.00331view →
PDACDFSMedianIII,IV0.4940.249.01519view →
CCRCCDFSTertileIV0.1880.948.02413view →
LUADOSMedianII,III,IV0.4630.756.0472view →
LSCCDFSMedianAll0.9051.000.0481view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ELP6–GBM (DFS)

Kaplan–Meier survival curve for ELP6 mass-spec protein-high vs -low samples in GBM.

Open the GBM breakdown →

Exploration