ELP6

Across TCGA cell cohorts, ELP6 mutation is significantly associated with the mutation status of many other genes, with 219 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ELP6-associated genes across cancer lineages are FOXN3, CDC40, and PGBD2. Each is linked with ELP6 in more than 1 cancer types. Because this analysis shows association rather than direction, both ELP6-to-partner and partner-to-ELP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FOXN3 grouped by ELP6-low versus ELP6-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELP6→partner) and Y-score (partner→ELP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	FOXN3 →	+5.297	+5.297	.004	.004	1	2
BLOOD_Leukemia	CDC40 →	+5.321	+5.894	.002	.002	1	2
BLOOD_Leukemia	PGBD2 →	+4.321	+5.285	.005	.005	1	2
BLOOD_Leukemia	PIK3R4 →	+4.321	+5.285	.005	.005	1	2
BLOOD_Leukemia	GPR89A →	+4.736	+5.560	.003	.003	1	2
BREAST	MICALL1 →	+4.297	+4.857	.009	.009	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 219 associations by consensus.

FOXN3 by ELP6 expression — BREAST

Explore this box plot interactively →