ELP4

Across TCGA pan-cancer cohorts, ELP4 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated ELP4 data layer compared with 23 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher ELP4 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated ELP4 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

UCEC, CCRCC, and PDAC are the cancer types where ELP4 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	II,III,IV	0.448	0.944	.002	24	view →
CCRCC	DFS	Tertile	All	1.000	0.856	.018	9	view →
PDAC	OS	Median	All	0.410	0.560	.042	6	view →
HNSC	DFS	Tertile	All	0.697	0.864	.049	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

ELP4–UCEC (DFS)

Open the UCEC breakdown →