ELP3

Across TCGA pan-cancer cohorts, ELP3 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated ELP3 data layer compared with 26 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher ELP3 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated ELP3 expression acts as an unfavorable survival marker, although some lineages such as UCEC and HNSC show a favorable association.

UCEC, PDAC, and HNSC are the cancer types where ELP3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	All	1.000	0.898	.004	18	view →
PDAC	DFS	Median	II,III,IV	0.717	0.833	.023	13	view →
HNSC	OS	Quartile	III,IV	0.878	0.494	.008	11	view →
CCRCC	OS	Median	III,IV	0.688	0.874	.008	5	view →
LSCC	OS	Quartile	III,IV	0.620	0.943	.045	2	view →
GBM	OS	Median	All	0.917	0.799	.012	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

ELP3–UCEC (OS)

Open the UCEC breakdown →