ELP3

Across TCGA patient cohorts, ELP3 mutation is significantly associated with the RNA expression of many other genes, with 2,724 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ELP3-associated genes across cancer lineages are EIF2S2P7, RNA5SP411, and SNORA10B. Each is linked with ELP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ELP3-to-partner and partner-to-ELP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EIF2S2P7 grouped by ELP3-low versus ELP3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELP3→partner) and Y-score (partner→ELP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EIF2S2P7 →	+0.064	+2.599	<.001	<.001	3	2
LUSC	RNA5SP411 →	+1.212	+5.148	<.001	.002	3	2
SKCM	SNORA10B →	+0.365	+4.979	<.001	<.001	3	2
SKCM	RNU6-18P →	+0.219	+5.219	<.001	.002	3	2
UCEC	MIR520H →	+0.213	+2.997	<.001	.001	3	2
UCEC	SC4MOP →	+0.033	+3.252	.008	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,724 associations by consensus.

EIF2S2P7 by ELP3 expression — UCEC

Explore this box plot interactively →