ELP1

Across TCGA cell cohorts, ELP1 mutation is significantly associated with the RNA expression of many other genes, with 56 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ELP1-associated genes across cancer lineages are ST8SIA3, PRORY, and DAZ3. Each is linked with ELP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ELP1-to-partner and partner-to-ELP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ST8SIA3 grouped by ELP1-low versus ELP1-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELP1→partner) and Y-score (partner→ELP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	ST8SIA3 →	+0.053	+4.807	<.001	.006	3	1
BLOOD_Myeloma	PRORY →	+1.180	+4.807	<.001	.006	3	1
BLOOD_Myeloma	DAZ3 →	+1.563	+4.807	<.001	.006	3	1
LUNG_NSCLC_LUSC	MC3R →	+0.446	+4.108	.009	.005	3	1
LUNG_SCLC	OR2T2 →	+0.023	+5.643	<.001	.002	3	1
BREAST	BHLHA9 →	+0.025	+3.836	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 56 associations by consensus.

ST8SIA3 by ELP1 expression — BLOOD_Myeloma

Explore this box plot interactively →