ELOVL7

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, ELOVL7 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated ELOVL7 data layer compared with 26 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher ELOVL7 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated ELOVL7 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

PDAC, GBM, and HNSC are the cancer types where ELOVL7 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
PDACDFSMedianII,III,IV0.4970.896.0076view →
GBMOSMedianAll0.3220.606.0402view →
HNSCOSMedianIV0.5270.866.0432view →
CCRCCDFSTertileAll1.0000.706.0241view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

ELOVL7–PDAC (DFS)

Kaplan–Meier survival curve for ELOVL7 mass-spec protein-high vs -low samples in PDAC.

Open the PDAC breakdown →

Exploration