ELOVL7

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ELOVL7 mutation is significantly associated with the RNA expression of many other genes, with 3,381 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ELOVL7-associated genes across cancer lineages are PCCA-DT, SNRPD3, and CRYBB2P1. Each is linked with ELOVL7 in more than 1 cancer types. Because this analysis shows association rather than direction, both ELOVL7-to-partner and partner-to-ELOVL7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCCA-DT grouped by ELOVL7-low versus ELOVL7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELOVL7→partner) and Y-score (partner→ELOVL7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECPCCA-DT →+0.605+2.223<.001<.00132
UCECSNRPD3 →+0.335+1.874.001.00232
UCECCRYBB2P1 →+0.565+2.606<.001<.00132
UCECRBBP8 →+0.672+3.711<.001<.00132
UCECCYB5B →+0.416+1.606.005.00632
UCECPSMD7 →+0.449+2.439.002.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,381 associations by consensus.

PCCA-DT by ELOVL7 expression — UCEC

Box plot of PCCA-DT in ELOVL7-low vs ELOVL7-high samples in UCEC.

Explore this box plot interactively →

Exploration