ELOVL5

Across TCGA patient cohorts, ELOVL5 mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ELOVL5-associated genes across cancer lineages are STAT3_pY705, eIF4G, and ERK2. Each is linked with ELOVL5 in more than 1 cancer types. Because this analysis shows association rather than direction, both ELOVL5-to-partner and partner-to-ELOVL5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, STAT3_pY705 grouped by ELOVL5-low versus ELOVL5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELOVL5→partner) and Y-score (partner→ELOVL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	STAT3_pY705 →	-0.495	-2.700	<.001	.005	3	2
UCEC	eIF4G →	+0.311	+3.169	.015	.018	3	1
UCEC	ERK2 →	+0.192	+1.807	.015	.027	3	1
UCEC	ACC1 →	+0.336	+3.183	.025	.009	3	1
UCEC	JNK_pT183_Y185 →	-0.205	-3.321	.003	.010	3	1
UCEC	Ku80 →	+0.228	+2.335	.019	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

STAT3_pY705 by ELOVL5 expression — UCEC

Explore this box plot interactively →