ELOVL5

Across TCGA cell cohorts, ELOVL5 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ELOVL5-associated genes across cancer lineages are PDHA2, TMCO5A, and OR2V1. Each is linked with ELOVL5 in more than 1 cancer types. Because this analysis shows association rather than direction, both ELOVL5-to-partner and partner-to-ELOVL5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PDHA2 grouped by ELOVL5-low versus ELOVL5-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELOVL5→partner) and Y-score (partner→ELOVL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	PDHA2 →	+0.033	+5.029	<.001	.006	3	1
LARGE_INTESTINE	TMCO5A →	+0.019	+4.415	<.001	.007	3	1
LARGE_INTESTINE	OR2V1 →	+0.042	+4.095	.004	.009	3	1
LARGE_INTESTINE	CFHR2 →	+0.057	+5.022	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

PDHA2 by ELOVL5 expression — LUNG_SCLC

Explore this box plot interactively →