ELOVL4

Across TCGA patient cohorts, ELOVL4 mutation is significantly associated with the total protein of many other genes, with 28 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ELOVL4-associated genes across cancer lineages are Ku80, 14-3-3_beta, and ACC_pS79. Each is linked with ELOVL4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ELOVL4-to-partner and partner-to-ELOVL4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ku80 grouped by ELOVL4-low versus ELOVL4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELOVL4→partner) and Y-score (partner→ELOVL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Ku80 →	+0.214	+1.527	.007	.009	3	2
UCEC	14-3-3_beta →	-0.083	-2.195	.015	.009	3	1
UCEC	ACC_pS79 →	+0.278	+1.495	.018	.034	3	1
UCEC	GSK-3a-b_pS21_S9 →	+0.366	+1.807	.011	.004	3	1
UCEC	JNK2 →	+0.187	+3.594	.005	.001	3	1
UCEC	MEK1 →	+0.396	+2.502	.001	.001	2	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

Ku80 by ELOVL4 expression — UCEC

Explore this box plot interactively →