ELOVL4

Across TCGA cell cohorts, ELOVL4 mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ELOVL4-associated genes across cancer lineages are SNPH, PTGFR, and FNDC9. Each is linked with ELOVL4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ELOVL4-to-partner and partner-to-ELOVL4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNPH grouped by ELOVL4-low versus ELOVL4-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELOVL4→partner) and Y-score (partner→ELOVL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SNPH →	+1.160	+3.215	<.001	.009	3	1
LARGE_INTESTINE	PTGFR →	+0.119	+3.478	.009	.002	3	1
LARGE_INTESTINE	FNDC9 →	+0.058	+2.637	<.001	.006	3	1
LARGE_INTESTINE	TECRL →	+0.009	+2.977	.001	.006	3	1
LARGE_INTESTINE	GAS2L2 →	+0.068	+3.070	.004	.002	3	1
LARGE_INTESTINE	OR12D2 →	+0.047	+2.560	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

SNPH by ELOVL4 expression — LARGE_INTESTINE

Explore this box plot interactively →