ELOVL3

Across TCGA patient cohorts, ELOVL3 mutation is significantly associated with the RNA expression of many other genes, with 2,172 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ELOVL3-associated genes across cancer lineages are MIR7976, RNA5SP411, and LINC02654. Each is linked with ELOVL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ELOVL3-to-partner and partner-to-ELOVL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR7976 grouped by ELOVL3-low versus ELOVL3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELOVL3→partner) and Y-score (partner→ELOVL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR7976 →	+0.337	+2.316	.003	.007	3	2
UCEC	RNA5SP411 →	+1.259	+2.031	<.001	.007	3	2
BRCA	LINC02654 →	+0.063	+5.382	<.001	.003	3	2
SKCM	GNG5 →	+0.430	+3.328	.009	.005	3	2
SKCM	BTBD6 →	+0.592	+3.198	.004	.009	3	2
UCEC	GAS2L1 →	+0.524	+2.807	.004	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,172 associations by consensus.

MIR7976 by ELOVL3 expression — UCEC

Explore this box plot interactively →