ELOVL1

Across TCGA pan-cancer cohorts, ELOVL1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated ELOVL1 data layer compared with 23 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ELOVL1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated ELOVL1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and COAD show a favorable association.

HNSC, COAD, and CCRCC are the cancer types where ELOVL1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Quartile	All	0.908	0.486	.001	64	view →
COAD	DFS	Median	III,IV	1.000	0.898	.043	12	view →
CCRCC	OS	Median	All	0.660	1.000	.009	12	view →
PDAC	OS	Tertile	II,III,IV	0.590	0.298	.022	11	view →
GBM	DFS	Quartile	All	0.278	0.410	.040	4	view →
LSCC	DFS	Quartile	II,III,IV	0.252	0.888	.024	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

ELOVL1–HNSC (DFS)

Open the HNSC breakdown →