ELOVL1

Across TCGA patient cohorts, ELOVL1 mutation is significantly associated with the total protein of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ELOVL1-associated genes across cancer lineages are PCNA, Smac, and JNK_pT183_Y185. Each is linked with ELOVL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ELOVL1-to-partner and partner-to-ELOVL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCNA grouped by ELOVL1-low versus ELOVL1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELOVL1→partner) and Y-score (partner→ELOVL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCNA →	+0.324	+3.000	.004	.036	3	2
UCEC	Smac →	+0.299	+3.321	.028	.010	3	2
UCEC	JNK_pT183_Y185 →	-0.208	-3.308	.018	.010	3	1
UCEC	JNK2 →	+0.388	+3.026	<.001	.018	3	1
UCEC	MEK1 →	+0.423	+3.321	.027	.010	3	1
UCEC	Bax →	+0.385	+3.009	.002	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

PCNA by ELOVL1 expression — UCEC

Explore this box plot interactively →