ELOF1

Across TCGA patient cohorts, ELOF1 mutation is significantly associated with the RNA expression of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ELOF1-associated genes across cancer lineages are RNA5SP259, RNU1-74P, and RNU6-952P. Each is linked with ELOF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ELOF1-to-partner and partner-to-ELOF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP259 grouped by ELOF1-low versus ELOF1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELOF1→partner) and Y-score (partner→ELOF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNA5SP259 →	+0.397	+5.103	<.001	.008	3	1
CESC	RNU1-74P →	+0.290	+5.969	<.001	.002	3	1
CESC	RNU6-952P →	+0.409	+5.306	<.001	.006	3	1
CESC	MIR1827 →	+0.613	+5.306	<.001	.006	3	1
CESC	NUP35P1 →	+0.060	+5.669	<.001	.003	3	1
CESC	MTATP6P21 →	+0.265	+5.418	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

RNA5SP259 by ELOF1 expression — CESC

Explore this box plot interactively →