Across TCGA pan-cancer cohorts, ELOA3P RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of ELOA3P’s most consistent transcriptional readouts.
The strongest signal is observed in thyroid carcinoma (THCA), where ELOA3P RNA is repressed in tumor relative to normal tissue. In most cancer types ELOA3P is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.
THCA are the cancer types where ELOA3P tumor–normal differential expression is most reproducible.