Across TCGA patient cohorts, ELOA2 mutation is significantly associated with the RNA expression of many other genes, with 7,247 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ELOA2-associated genes across cancer lineages are MRPL43, CRYBB2P1, and PRMT5. Each is linked with ELOA2 in more than 4 cancer types. Because this analysis shows association rather than direction, both ELOA2-to-partner and partner-to-ELOA2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELOA2→partner) and Y-score (partner→ELOA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	MRPL43 →	+0.390	+3.503	.002	.002	3	5
UCEC	CRYBB2P1 →	+0.396	+1.800	<.001	.003	3	4
UCEC	PRMT5 →	+0.618	+3.180	<.001	<.001	3	4
UCEC	GPN3 →	+0.618	+2.007	<.001	<.001	3	4
UCEC	GMNN →	+0.615	+1.758	<.001	<.001	3	4
COAD	DYNC2I2 →	+0.444	+2.827	.004	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,247 associations by consensus.

Exploration

ELOA2 survival (RNA) · tumor vs normal (RNA) · all ELOA2 data types