ELOA2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ELOA2 mutation is significantly associated with the RNA expression of many other genes, with 577 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ELOA2-associated genes across cancer lineages are OR3A2, TRIM60, and GPX6. Each is linked with ELOA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ELOA2-to-partner and partner-to-ELOA2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELOA2→partner) and Y-score (partner→ELOA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OESOPHAGUSOR3A2 →+0.030+4.906<.001.00631
BREASTTRIM60 →+0.466+5.169<.001.00531
BREASTGPX6 →+0.012+5.169<.001.00531
BLOOD_LymphomaSEL1L2 →+0.011+4.643.004.00531
BLOOD_LymphomaBPIFA2 →+0.943+4.191<.001.00731
BLOOD_LymphomaCYP7A1 →+0.031+4.191<.001.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 577 associations by consensus.

Exploration