ELOA-AS1

Across TCGA pan-cancer cohorts, ELOA-AS1 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of ELOA-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where ELOA-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types ELOA-AS1 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

THCA, HNSC, and BLCA are the cancer types where ELOA-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ELOA-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	III,IV	−0.647	<.001	11	view →
HNSC	Male	IV	+0.704	<.001	10	view →
BLCA	All	All	+0.551	.001	8	view →
LUSC	Female	II,III,IV	+0.962	<.001	7	view →
COAD	Male	All	+0.603	<.001	7	view →
KIRC	All	All	+0.163	.003	7	view →
KICH	Female	All	−0.918	<.001	6	view →
LUAD	All	All	+0.279	.002	4	view →
STAD	All	All	+0.366	.006	3	view →
READ	All	All	+0.541	.021	2	view →
UCEC	All	III,IV	+0.507	.026	2	view →
LIHC	Male	All	+0.486	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

ELOA-AS1–THCA

Open the THCA breakdown →