ELN

Across TCGA patient cohorts, ELN RNA expression is significantly associated with the protein abundance of many other proteins, with 22,683 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible ELN-associated proteins across cancer lineages are NEXN_S365, PRKG1, and KANK2_S375. Each is linked with ELN in more than 8 cancer types. Because this analysis shows association rather than direction, both ELN-to-partner and partner-to-ELN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ELN versus NEXN_S365 in CCRCC, with a Pearson correlation of 0.68.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ELN→partner) and Y-score (partner→ELN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	NEXN_S365 →	+1.151	+1.253	<.001	<.001	3	9
UCEC	PRKG1 →	+0.782	+0.770	<.001	.002	3	9
UCEC	KANK2_S375 →	+0.678	+0.800	<.001	<.001	3	9
OV	LMCD1 →	+0.626	+1.483	<.001	<.001	3	9
CCRCC	LMOD1 →	+1.160	+1.600	<.001	<.001	3	9
CCRCC	LMOD1_S85 →	+1.330	+1.608	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,683 associations by consensus.

ELN vs NEXN_S365 — CCRCC

Explore this scatter interactively →