ELMOD3

Across TCGA patient cohorts, ELMOD3 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ELMOD3-associated genes across cancer lineages are pDC, CD8+ naive T-cells, and Endothelial cells. Each is linked with ELMOD3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ELMOD3-to-partner and partner-to-ELMOD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, pDC grouped by ELMOD3-low versus ELMOD3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELMOD3→partner) and Y-score (partner→ELMOD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	pDC →	+0.045	+2.202	.040	.033	3	2
UCEC	CD8+ naive T-cells →	+0.030	+3.032	.013	.018	3	1
UCEC	Endothelial cells →	-0.037	-1.957	.029	.032	3	1
UCEC	Th2 cells →	+0.259	+2.329	.001	.020	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

pDC by ELMOD3 expression — UCEC

Explore this box plot interactively →