ELMOD2

Across TCGA pan-cancer cohorts, ELMOD2 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of ELMOD2’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where ELMOD2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ELMOD2 is over-expressed in tumor, although a few such as THCA and COAD show the opposite, repressed pattern.

KIRC, HNSC, and LIHC are the cancer types where ELMOD2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ELMOD2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	IV	+0.888	<.001	12	view →
HNSC	All	III,IV	+0.554	<.001	11	view →
LIHC	Female	II,III,IV	+0.708	<.001	9	view →
THCA	Male	III,IV	−0.705	<.001	9	view →
KIRP	All	II,III,IV	+0.661	<.001	9	view →
STAD	All	II,III,IV	+0.665	.001	7	view →
LUAD	Male	All	+0.508	<.001	6	view →
BRCA	All	II,III,IV	+0.438	<.001	6	view →
CHOL	Male	All	+1.375	<.001	5	view →
COAD	Female	All	−0.675	.006	2	view →
BLCA	All	All	+0.334	.037	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

ELMOD2–KIRC

Open the KIRC breakdown →