ELMO2

Across TCGA cell cohorts, ELMO2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,646 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ELMO2-associated GO terms across cancer lineages are Endosomal transport, Cytosolic transport, and Vesicle-mediated transport to the plasma membrane. Each is linked with ELMO2 in more than 15 cancer types. Because this analysis shows association rather than direction, both ELMO2-to-partner and partner-to-ELMO2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal transport grouped by ELMO2-low versus ELMO2-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ELMO2→partner) and Y-score (partner→ELMO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Endosomal transport →	+0.056	+0.900	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Cytosolic transport →	+0.076	+0.782	.001	.004	3	16
STOMACH	Vesicle-mediated transport to the plasma membrane →	+0.078	+1.165	.002	.001	3	15
LUNG_NSCLC_LUSC	Negative regulation of organelle assembly →	+0.099	+0.951	.004	.002	3	15
UPPER_AERODIGESTIVE_TRACT	Cytokinesis →	+0.070	+0.793	<.001	<.001	3	14
STOMACH	Response to oscillatory fluid shear stress →	+0.157	+1.020	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,646 associations by consensus.

Endosomal transport by ELMO2 expression — LARGE_INTESTINE

Explore this box plot interactively →