ELMO2

Across TCGA cell cohorts, ELMO2 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ELMO2-associated genes across cancer lineages are ETNPPL, UTF1, and OR10W1. Each is linked with ELMO2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ELMO2-to-partner and partner-to-ELMO2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ETNPPL grouped by ELMO2-low versus ELMO2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELMO2→partner) and Y-score (partner→ELMO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ETNPPL →	+0.195	+4.021	.004	.001	3	1
LARGE_INTESTINE	UTF1 →	+0.015	+3.217	<.001	.006	3	1
LARGE_INTESTINE	OR10W1 →	+0.014	+3.562	<.001	.002	3	1
BLOOD_Leukemia	NPFFR1 →	+0.011	+4.037	.003	.004	3	1
BLOOD_Leukemia	C16orf92 →	+0.152	+4.037	<.001	.004	3	1
BLOOD_Leukemia	FAM71B →	+0.012	+4.060	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

ETNPPL by ELMO2 expression — LARGE_INTESTINE

Explore this box plot interactively →