ELMO1

Across TCGA patient cohorts, ELMO1 mutation is significantly associated with the RNA expression of many other genes, with 5,509 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ELMO1-associated genes across cancer lineages are GEMIN2, MIR4427, and SNRNP40. Each is linked with ELMO1 in more than 3 cancer types. Because this analysis shows association rather than direction, both ELMO1-to-partner and partner-to-ELMO1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GEMIN2 grouped by ELMO1-low versus ELMO1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELMO1→partner) and Y-score (partner→ELMO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GEMIN2 →	+0.398	+1.733	<.001	<.001	3	4
CESC	MIR4427 →	+0.401	+3.381	<.001	.003	3	3
UCEC	SNRNP40 →	+0.500	+1.572	<.001	<.001	3	3
SKCM	RN7SL117P →	+0.011	+3.816	<.001	.005	3	3
UCEC	SLC2A13 →	+0.298	+1.571	.002	.004	3	3
UCEC	SUPV3L1 →	+0.407	+2.373	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,509 associations by consensus.

GEMIN2 by ELMO1 expression — UCEC

Explore this box plot interactively →