ELL3

Across TCGA patient cohorts, ELL3 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,156 significant associations in total. LIHC shows the largest number of these associations.

The most reproducible ELL3-associated GO terms across cancer lineages are DNA synthesis involved in DNA repair, Protein transmembrane import into intracellular organelle, and Centriole assembly. Each is linked with ELL3 in more than 23 cancer types. Because this analysis shows association rather than direction, both ELL3-to-partner and partner-to-ELL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA synthesis involved in DNA repair grouped by ELL3-low versus ELL3-high in THYM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ELL3→partner) and Y-score (partner→ELL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	DNA synthesis involved in DNA repair →	+0.060	+0.303	<.001	<.001	3	24
THYM	Protein transmembrane import into intracellular organelle →	+0.060	+0.553	<.001	<.001	3	23
ACC	Centriole assembly →	+0.042	+0.208	<.001	<.001	3	22
CHOL	Telomere maintenance →	+0.034	+0.726	<.001	.001	3	22
CHOL	Recombinational repair →	+0.030	+0.853	.002	.001	2	23
UVM	tRNA processing →	+0.036	+0.304	<.001	<.001	3	22

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,156 associations by consensus.

DNA synthesis involved in DNA repair by ELL3 expression — THYM

Explore this box plot interactively →