ELL3

Across TCGA patient cohorts, ELL3 protein abundance is significantly associated with the RNA expression of many other genes, with 4,948 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ELL3-associated genes across cancer lineages are LPIN2, TBL1X, and SLC25A15. Each is linked with ELL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ELL3-to-partner and partner-to-ELL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ELL3 versus LPIN2 in CCRCC, with a Pearson correlation of -0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELL3→partner) and Y-score (partner→ELL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	LPIN2 →	-0.731	-0.597	.002	<.001	3	1
CCRCC	TBL1X →	+0.580	+0.415	.008	.009	3	1
CCRCC	SLC25A15 →	-0.489	-0.399	.002	.009	3	1
CCRCC	TRPS1 →	-0.839	-0.461	<.001	<.001	3	1
CCRCC	CAV2 →	+0.606	+0.416	<.001	<.001	3	1
CCRCC	CAV1 →	+0.806	+0.367	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,948 associations by consensus.

ELL3 vs LPIN2 — CCRCC

Explore this scatter interactively →