ELL3

Across TCGA cell cohorts, ELL3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,022 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ELL3-associated GO terms across cancer lineages are Regulation of collagen metabolic process, Fibrinolysis, and Regulation of blood coagulation. Each is linked with ELL3 in more than 11 cancer types. Because this analysis shows association rather than direction, both ELL3-to-partner and partner-to-ELL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of collagen metabolic process grouped by ELL3-low versus ELL3-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ELL3→partner) and Y-score (partner→ELL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Regulation of collagen metabolic process →	-0.156	-1.374	.001	.002	3	12
BREAST	Fibrinolysis →	-1.485	-1.296	<.001	<.001	3	11
BREAST	Regulation of blood coagulation →	-0.144	-1.535	<.001	.001	2	11
LUNG_NSCLC_LUSC	Establishment of epithelial cell apical/basal polarity →	-0.207	-1.298	<.001	<.001	3	10
SOFT_TISSUE	Substrate adhesion-dependent cell spreading →	-0.136	-1.220	<.001	<.001	3	10
SOFT_TISSUE	Bundle of His cell to Purkinje myocyte communication →	+0.899	+2.240	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,022 associations by consensus.

Regulation of collagen metabolic process by ELL3 expression — LIVER

Explore this box plot interactively →