ELL3

Across TCGA cell cohorts, ELL3 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ELL3-associated genes across cancer lineages are TAS2R7, OR4D1, and OR5C1. Each is linked with ELL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ELL3-to-partner and partner-to-ELL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAS2R7 grouped by ELL3-low versus ELL3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELL3→partner) and Y-score (partner→ELL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TAS2R7 →	+0.014	+4.437	<.001	.004	3	1
LARGE_INTESTINE	OR4D1 →	+0.005	+4.217	.006	.001	3	1
LARGE_INTESTINE	OR5C1 →	+0.033	+3.793	.008	.007	3	1
LARGE_INTESTINE	BPIFB6 →	+0.020	+4.437	<.001	.004	3	1
LARGE_INTESTINE	GAGE12H →	+0.066	+4.437	<.001	.004	3	1
LARGE_INTESTINE	TMEM233 →	+0.357	+4.196	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

TAS2R7 by ELL3 expression — LARGE_INTESTINE

Explore this box plot interactively →