ELK4

Across TCGA patient cohorts, ELK4 protein abundance is significantly associated with the RNA expression of many other genes, with 659 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ELK4-associated genes across cancer lineages are GRB10, FZD8, and LGALS3BP. Each is linked with ELK4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ELK4-to-partner and partner-to-ELK4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ELK4 versus GRB10 in BRCA, with a Pearson correlation of -0.71.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELK4→partner) and Y-score (partner→ELK4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GRB10 →	-1.068	-0.505	<.001	<.001	3	2
BRCA	FZD8 →	-1.574	-0.586	.006	.006	3	2
LUAD	LGALS3BP →	+0.616	+0.378	.007	.009	3	1
LUAD	ID2 →	+0.709	+0.394	<.001	.004	3	1
LUAD	RPL22 →	+0.570	+0.500	.006	.007	3	1
LUAD	FRS3 →	-0.453	-0.276	.002	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 659 associations by consensus.

ELK4 vs GRB10 — BRCA

Explore this scatter interactively →