ELK3

Across TCGA pan-cancer cohorts, ELK3 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated ELK3 data layer compared with 27 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher ELK3 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated ELK3 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

CCRCC, LUAD, and LSCC are the cancer types where ELK3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Tertile	All	1.000	0.404	.001	26	view →
LUAD	DFS	Quartile	All	0.175	0.798	.003	18	view →
LSCC	DFS	Quartile	III,IV	0.305	0.969	.013	8	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

ELK3–CCRCC (DFS)

Open the CCRCC breakdown →