ELK1

Across TCGA pan-cancer cohorts, ELK1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated ELK1 data layer compared with 21 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher ELK1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated ELK1 expression acts as an unfavorable survival marker.

LSCC, HNSC, and PDAC are the cancer types where ELK1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Median	II,III,IV	0.756	0.958	.011	15	view →
HNSC	OS	Tertile	III,IV	0.568	0.950	.017	6	view →
PDAC	DFS	Median	II,III,IV	0.291	0.770	.024	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

ELK1–LSCC (OS)

Open the LSCC breakdown →