ELK1

Across TCGA patient cohorts, ELK1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,416 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ELK1-associated proteins across cancer lineages are GRIPAP1, HUWE1, and MSH2. Each is linked with ELK1 in more than 4 cancer types. Because this analysis shows association rather than direction, both ELK1-to-partner and partner-to-ELK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ELK1 versus GRIPAP1 in OV, with a Pearson correlation of 0.55.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ELK1→partner) and Y-score (partner→ELK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	GRIPAP1 →	+0.242	+0.407	<.001	<.001	3	5
OV	HUWE1 →	+0.337	+0.707	<.001	<.001	3	5
LSCC	MSH2 →	+0.313	+0.290	.003	<.001	3	4
CCRCC	PLOD1 →	+0.488	+0.320	<.001	<.001	3	4
LSCC	XPO1 →	+0.189	+0.260	<.001	.002	3	4
LSCC	MAGED2 →	+0.351	+0.346	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,416 associations by consensus.

ELK1 vs GRIPAP1 — OV

Explore this scatter interactively →