ELFN2

Across TCGA patient cohorts, ELFN2 mutation is significantly associated with the total protein of many other genes, with 62 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ELFN2-associated genes across cancer lineages are Src_pY527, AR, and ATM. Each is linked with ELFN2 in more than 2 cancer types. Because this analysis shows association rather than direction, both ELFN2-to-partner and partner-to-ELFN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Src_pY527 grouped by ELFN2-low versus ELFN2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELFN2→partner) and Y-score (partner→ELFN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Src_pY527 →	-0.325	-1.652	.007	.010	3	3
UCEC	AR →	-0.283	-0.947	.006	.047	3	3
UCEC	ATM →	-0.352	-1.273	.005	.007	3	3
STAD	TFRC →	+0.849	+3.169	.003	.017	3	2
STAD	Cyclin-B1 →	+0.616	+3.321	.004	.010	3	2
STAD	Cyclin-E2 →	+0.206	+3.190	.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 62 associations by consensus.

Src_pY527 by ELFN2 expression — UCEC

Explore this box plot interactively →