ELFN2

Across TCGA cell cohorts, ELFN2 mutation is significantly associated with the RNA expression of many other genes, with 527 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ELFN2-associated genes across cancer lineages are GALR3, TMEM235, and SLC36A3. Each is linked with ELFN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ELFN2-to-partner and partner-to-ELFN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GALR3 grouped by ELFN2-low versus ELFN2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELFN2→partner) and Y-score (partner→ELFN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GALR3 →	+0.086	+2.646	<.001	.006	3	2
STOMACH	TMEM235 →	+0.009	+3.794	<.001	.003	3	1
LUNG_SCLC	SLC36A3 →	+0.012	+3.169	.001	.005	3	1
LUNG_SCLC	CCDC196 →	+0.034	+3.058	<.001	.004	3	1
LUNG_SCLC	PRAMEF6 →	+0.008	+3.614	<.001	.001	3	1
LUNG_SCLC	GAGE2E →	+2.389	+3.263	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 527 associations by consensus.

GALR3 by ELFN2 expression — LARGE_INTESTINE

Explore this box plot interactively →