ELFN1

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ELFN1 mutation is significantly associated with the total protein of many other genes, with 40 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ELFN1-associated genes across cancer lineages are 14-3-3_beta, Shc_pY317, and JNK_pT183_Y185. Each is linked with ELFN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ELFN1-to-partner and partner-to-ELFN1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELFN1→partner) and Y-score (partner→ELFN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COAD14-3-3_beta →-0.169-2.559.048.01132
COADShc_pY317 →-0.154-2.983.028.03432
UCECJNK_pT183_Y185 →-0.144-1.362.007.03432
UCECCaspase-7-cleavedD198 →+0.605+1.999.001.00832
UCEC4E-BP1 →+0.244+2.115.004.01632
UCECDi-Ras3 →-0.134-2.893.004.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

Exploration