ELF3

Across TCGA patient cohorts, ELF3 mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible ELF3-associated genes across cancer lineages are SF2, G6PD, and PI3K-p110-a. Each is linked with ELF3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ELF3-to-partner and partner-to-ELF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SF2 grouped by ELF3-low versus ELF3-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELF3→partner) and Y-score (partner→ELF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	SF2 →	+0.137	+3.000	.048	.034	3	2
BLCA	G6PD →	-0.356	-1.861	.030	.049	3	1
BLCA	PI3K-p110-a →	-0.117	-2.415	.008	.003	3	1
BLCA	PI3K-p85 →	-0.138	-2.446	.043	.018	3	1
BLCA	GATA3 →	+0.550	+2.584	.007	.010	2	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

SF2 by ELF3 expression — BLCA

Explore this box plot interactively →