ELF3

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ELF3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,784 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ELF3-associated GO terms across cancer lineages are Regulation of hippocampal neuron apoptotic process, Negative regulation of hippocampal neuron apoptotic process, and Mammary gland development. Each is linked with ELF3 in more than 14 cancer types. Because this analysis shows association rather than direction, both ELF3-to-partner and partner-to-ELF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of hippocampal neuron apoptotic process grouped by ELF3-low versus ELF3-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ELF3→partner) and Y-score (partner→ELF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
URINARY_TRACTRegulation of hippocampal neuron apoptotic process →+1.706+5.461.001<.001315
URINARY_TRACTNegative regulation of hippocampal neuron apoptotic process →+1.585+5.461.001<.001314
STOMACHMammary gland development →+0.168+4.030<.001<.001314
LUNG_NSCLC_LUADProtein transport into membrane raft →+0.619+3.563<.001<.001312
STOMACHUDP-galactose transmembrane transport →+0.160+3.602<.001<.001312
OVARYPositive regulation of iron ion transport →+1.833+2.989<.001<.001312
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,784 associations by consensus.

Regulation of hippocampal neuron apoptotic process by ELF3 expression — URINARY_TRACT

Box plot of Regulation of hippocampal neuron apoptotic process in ELF3-low vs ELF3-high samples in URINARY_TRACT.

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Exploration