ELF1

Across TCGA pan-cancer cohorts, ELF1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated ELF1 data layer compared with 21 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher ELF1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated ELF1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LUAD show a favorable association.

CCRCC, LUAD, and LSCC are the cancer types where ELF1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Tertile	III,IV	1.000	0.711	.002	54	view →
LUAD	DFS	Tertile	All	0.860	0.592	.001	28	view →
LSCC	DFS	Quartile	All	0.393	0.796	.002	20	view →
PDAC	DFS	Median	All	0.901	0.693	<.001	18	view →
GBM	DFS	Median	All	0.497	0.261	.009	8	view →
HNSC	DFS	Median	All	0.917	0.986	.006	5	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

ELF1–CCRCC (OS)

Open the CCRCC breakdown →