ELF1

Across TCGA patient cohorts, ELF1 mutation is significantly associated with the total protein of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ELF1-associated genes across cancer lineages are FoxM1, ACC1, and INPP4B. Each is linked with ELF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ELF1-to-partner and partner-to-ELF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FoxM1 grouped by ELF1-low versus ELF1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELF1→partner) and Y-score (partner→ELF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FoxM1 →	+0.293	+2.247	.002	.001	3	1
UCEC	ACC1 →	+0.273	+2.115	.041	.017	3	1
UCEC	INPP4B →	-0.267	-2.321	.024	.033	3	1
UCEC	ACVRL1 →	-0.139	-3.308	.005	.009	3	1
UCEC	JNK_pT183_Y185 →	-0.161	-1.874	.009	.049	3	1
UCEC	Ku80 →	+0.222	+2.261	.010	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

FoxM1 by ELF1 expression — UCEC

Explore this box plot interactively →