ELF1

Across TCGA cell cohorts, ELF1 mutation is significantly associated with the drug of many other genes, with 16 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ELF1-associated genes across cancer lineages are Mirin, LCL161, and GSK2801. Each is linked with ELF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ELF1-to-partner and partner-to-ELF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mirin grouped by ELF1-low versus ELF1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELF1→partner) and Y-score (partner→ELF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Mirin →	+0.442	+2.646	.019	.047	3	1
LARGE_INTESTINE	LCL161 →	+0.353	+2.646	.030	.047	3	1
LARGE_INTESTINE	GSK2801 →	+0.363	+2.649	.021	.046	3	1
LARGE_INTESTINE	Quizartinib →	+0.399	+2.652	.012	.045	3	1
LARGE_INTESTINE	Ara-G →	+0.179	+2.722	.034	.040	3	1
LARGE_INTESTINE	SGC-CBP30 →	+0.335	+2.649	.017	.046	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Mirin by ELF1 expression — LARGE_INTESTINE

Explore this box plot interactively →